Mitral Stenosis

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Quantification of mitral valve stenosis[1]

Slight Moderate Severe
PGmean <5mmHg 5-10mmHg >10mmHg
PHT <90m/s 90-150m/s >150m/s
MVA >1.5cm2 1.5-1cm2 <1cm2

Click here to calculate MVA by PHT

MS01.jpg
Moderate / severe MS

Various techniques can be used to estimate the severity of a mitral valve stenosis.

The peak pressure is unreliable for assessing the severity of mitral valve stenosis. Also, the pressure differential is strongly influenced by the heart rate. A high heart rate will greatly increase the pressure difference due to the strongly reduced duration of diastole. For heart rates between 60 - 90/min , the average gradient is estimated by "tracing" of the CW signal across the mitral.

Pressure half-time

By using an empirical formula the mitral valve area can be calculated using: MVA = 220/PHT.
MVPHT.png

Pitfalls:

In any situation where the LV diastolic pressure rises rapidly (AOI, non-compliant LV, myocardial ischemia) it will give an underestimation of the severity of mitral valve stenosis. Immediately after the balloon dilatation of the mitral valve the PHT method is unreliable. In tachycardia at which the A-top merges with the E-top or the atrial flutter waves the E-wave deformation may overestimate the incidence of mitral stenosis.

Heart rates of between 60 and 90/min give best results.

Continuity equation

The continuity equation can be used as the flow through the mitral valve is the same as the flow through the aortic valve and pulmonary valve (mitral valvular insufficiency and aortic valve insufficiency or absence of pulmonary valve insufficiency) .

MVA = TVI(lvot) x area (lvot) / TVI(mv)

Tracing the mitral valve surface

Also when tracing of the mitral valve surface is done, the result of this determination is highly dependent on the gain setting of the ultrasound device, and if it was the smallest opening of the mitral valve is traced. The results, therefore, they are less reliable and reproducible when compared with the calculated mitral valve surface. 3D - echo is more suitable to still make a reliable route, but it is, however, strongly dependent on the picture quality.

Assess suitability mitral plastic

Echocardiography can be predicted whether a patient develops a significant mitral valvular insufficiency after balloon angioplasty. Wilkins was the first to develop a score that the risk of an unsuccessful balloon angioplasty can be estimated.[2]

Click here for Wilkins score (also called Mitral Valvuloplasty score)

References

  1. Lancellotti P, Moura L, Pierard LA, Agricola E, Popescu BA, Tribouilloy C, Hagendorff A, Monin JL, Badano L, Zamorano JL, and European Association of Echocardiography. European Association of Echocardiography recommendations for the assessment of valvular regurgitation. Part 2: mitral and tricuspid regurgitation (native valve disease). Eur J Echocardiogr. 2010 May;11(4):307-32. DOI:10.1093/ejechocard/jeq031 | PubMed ID:20435783 | HubMed [1]
  2. Wilkins GT, Weyman AE, Abascal VM, Block PC, and Palacios IF. Percutaneous balloon dilatation of the mitral valve: an analysis of echocardiographic variables related to outcome and the mechanism of dilatation. Br Heart J. 1988 Oct;60(4):299-308. DOI:10.1136/hrt.60.4.299 | PubMed ID:3190958 | HubMed [2]

All Medline abstracts: PubMed | HubMed