Aortic Valve Stenosis

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Aortic stenosis quantification

Slight Moderate Severe
PG max 15-40 mmHg 40-70 mmHg 70-100 mmHg (> 100 mmHg severe AoS)
PG mean <20mmHg 20-40mmHg> 40mmHg
AVA> 1.5cm2 1.5-1cm2 <1cm2
Dimensionless index> 0.50 0.25 to 0.50 <0.25
Vmax <3m/s 3-4m/s >4m/s
AVA BSAindex >0.85cm2/m2 0.85-0.60cm2/m2 <0.60cm2/m2
AoScw03.jpg Video
Serious AoS: PG max 101mmHg, PG mean 69mmHg[1] PHT moderate Aol [1]
Click here to calculate AGM

Aortic valve area (AVA)

For the calculation of the aortic valve surface, the continuity equation can be applied.

Continuity equation: A1.v1 = A2.v2
Continuty equation.svg
Where: A=area (∏r2) cm2
v=velocity, cm/s (can be used as maximum speed or TVI)
so:

Aortic valve area (AVA)=( D LVOT/2 )2 x 3:14 x Vmax LVOT/Vmax peak in AoS jet

Where: D LVOT=diameter LVOT in cm

Dimensionless index (DI)

If you are unable to get a good measurement of the LVOT can also the ratio of the velocity in the LVOT and the speed of the aortic valve to give a good impression about the severity of aortic stenosis .

DI = V LVOT/V aorta

In a DI ≤25, there is almost always a severe aortic valve stenosis .

Low-gradient aortic stenosis vs . Pseudo stenosis

In an aortic valve stenosis with a low gradient (< 30 mmHg), and poor left ventricular function is to be a valve surface calculated . If an AVA <1 cm2 is calculated can be a severe aortic valve stenosis are present despite the low gradient. However, it could also be that the valve does not open properly due to low cardiac output (pseudo stenosis). To gain more insight into the aortic valve or a "true" or stenosis has a "pseudo stenosis" seems dobutamine stress worthwhile. If during dobutamine infusion up to 20 μg/kg there is an increase of more than 20% in the VTI of the LVOT (ie cardiac output ) and the calculated valve area remains below 1 cm2 then there is a true aortic stenosis . If not , and there appears to be a contractile reserve (which is predictive of a better prognosis after aortic valve replacement ) it is called a pseudo stenosis.

References

  1. Baumgartner H, Hung J, Bermejo J, Chambers JB, Evangelista A, Griffin BP, Iung B, Otto CM, Pellikka PA, Quiñones M, and EAE/ASE. Echocardiographic assessment of valve stenosis: EAE/ASE recommendations for clinical practice. Eur J Echocardiogr. 2009 Jan;10(1):1-25. DOI:10.1093/ejechocard/jen303 | PubMed ID:19065003 | HubMed [1]